Progress in cardiovascular diseases
Efficacy and safety of cardiac myosin inhibitors in obstructive hypertrophic cardiomyopathy: Systematic review and comprehensive frequentist and Bayesian meta-analyses of Phase 3 randomized controlled trials.
Matthew M Y Lee, Fraser C Goldie, Alasdair D Henderson, Ahmad Masri, Iacopo Olivotto, Caroline J Coats
Published: 202510.1016/j.pcad.2025.10.002
Abstract
AIMS: Data on cardiac myosin inhibitors (CMIs) in obstructive hypertrophic cardiomyopathy (oHCM) are rapidly emerging. This systematic review and meta-analysis evaluated the efficacy and safety of CMIs in randomized placebo-controlled trials. METHODS…
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