Progress in biophysics and molecular biology
Macromolecular crowding and protein aggregation: Friend, foe or contextual force?
Isabella V Gimón, Conner Sandefur, Santiago Schnell
Published: 202510.1016/j.pbiomolbio.2025.12.001
Abstract
Protein aggregation plays a dual role in cellular biology, enabling essential functions such as intracellular organization, signaling, and storage, while also contributing to pathological states associated with misfolding and toxicity. However, exist…
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