Pharmacology, biochemistry, and behaviorAnimalsAlzheimer DiseaseMiceInbred C57BLDisease Models
Long-term thiethylperazine treatment in the Tg4-42 mouse model of Alzheimer's disease mouse: Therapeutic potential vs. adverse effects.
Lisa Katharina Ruoff, Irina Wanda Helene Bänfer, Djavid Elias Liedtke, Sofie Elena China, Jens Wiltfang, Thomas A Bayer, Sören Frederik Bock, Friederike Spandau, Caroline Bouter, Nicola Beindorff, Yvonne Bouter
Published: 202610.1016/j.pbb.2025.174127
Abstract
BACKGROUND: Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive cognitive decline and behavioral impairments. Thiethylperazine, a dopamine receptor antagonist with antiemetic and antidopaminergic properties, has been…
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