Parkinsonism & related disordersHumansDNA RepairHuntington DiseasePhenotypeAnimals
Exploring the interaction between nucleotide excision repair pathways and Huntington disease: Implications for neurodegeneration and phenotypic overlap.
Gonzalez Rojas Natalia, Cesarini Martin Emiliano, Espindola Melisa, Gatto Emilia Mabel
Published: 202510.1016/j.parkreldis.2025.108091
Abstract
Under normal conditions DNA is constantly exposed to various endogenous and exogenous factors that induce DNA damage. To maintain and ensure its integrity, eukaryotic cells possess several complex DNA repair mechanisms. Each of these mechanisms is ac…
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