Parkinsonism & related disordersHumansCognitive DysfunctionParkinson DiseaseMaleFemale
Parkinson's disease mild cognitive impairment with MRI evidence of cholinergic nucleus 4 degeneration: A new subtype?
Ahmed Negida, Hiba Z Vohra, Sarah K Lageman, Nitai Mukhopadhyay, Brian D Berman, Daniel Weintraub, Matthew J Barrett
Published: 202510.1016/j.parkreldis.2025.108072
Abstract
BACKGROUND: Subtyping Parkinson's disease with mild cognitive impairment (PD-MCI) into clinically and pathologically homogeneous groups could improve clinical trials and enable personalized treatments. Cholinergic nucleus 4 (Ch4) degeneration has bee…
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