Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Comparative performance of 99mTc-pyrophosphate vs. 99mTc-hydroxymethylene diphosphonate for cardiac amyloid radionuclide imaging.
Gregorio Tersalvi, Patricia Carey, Armin Garmany, Christopher G Scott, Daniel R Davies, Hayan Jouni, Martin G Rodriguez-Porcel, J Wells Askew, John P Bois, Kathleen A Young, Nandan S Anavekar, Ian C Chang, Patricia A Pellikka, Martha Grogan, Angela Dispenzieri
Published: 202510.1016/j.nuclcard.2025.102587
Abstract
BACKGROUND: Cardiac amyloid radionuclide imaging (CARI) with 99mTc-pyrophosphate (PYP) enables the noninvasive diagnosis of transthyretin amyloid cardiomyopathy (ATTR-CM). Recent PYP shortages have necessitated substitution with 99mTc-hydroxymethylen…
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