NeuroscienceAnimalsHaploinsufficiencyMiceDNA-Binding ProteinsOxytocin
Autism-like behavior Increases with age and is predated by molecular changes in Arid1b haploinsufficient mice.
Thomas James L Ford, Byeong Tak Jeon, Hyunkyoung Lee, Woo-Yang Kim
Published: 202610.1016/j.neuroscience.2025.12.041
Abstract
Genetic studies have revealed that ARID1B haploinsufficiency leads to autism spectrum disorder (ASD). Given the dynamic development of the brain and behavior, understanding the critical developmental window that influences the onset and severity of A…
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