NeuroscienceHumansAlzheimer DiseasePolymorphismSingle NucleotideBiomarkers
Integrating multimodal data to identify single nucleotide polymorphism-related biomarkers and regulatory mechanisms in Alzheimer's disease.
Jinhua Sheng, Luyun Wang, Qiao Zhang, Jay Tsai Chien Chou, Rong Zhang, Tao Li, Yan Lu
Published: 202610.1016/j.neuroscience.2025.12.022
Abstract
Alzheimer's disease (AD) is the most common neurodegenerative disease with unclear regulatory mechanisms at the cell-type level. A multi-omics model called single nucleotide polymorphisms (SNPs)-transcriptomic-single-nucleus ribonucleic acid sequenci…
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