NeuroscienceKainic AcidHumansInduced Pluripotent Stem CellsNeuronsCerebral Cortex
In vitro identification of kainic acid-induced, concentration-dependent responses in human cortical neuronal networks.
Lotta Isosaari, Oskari Kulta, Satu Jäntti, Andrey Vinogradov, Elena Perez Morrissey, Ina Woods, Rachel Stewart, Jouni Sirviö, Fikret Emre Kapucu, Jochen H M Prehn, Susanna Narkilahti
Published: 202610.1016/j.neuroscience.2025.11.033
Abstract
Neuronal networks derived from human induced pluripotent stem cells (hiPSCs) have gained attention for their potential use in studying cellular electrophysiology. Similar to in vivo animal models of seizures and epilepsy, neuronal activity can be alt…
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