NeuropharmacologyHumansOrganoidsReceptorsPurinergic P2XCerebral Cortex
P2X purinergic receptors are required for correct cortical development in human brain organoids.
María Benito-León, Julia Serrano-López, Celia Llorente-Sáez, Marina Arribas-Blázquez, Luis A Olivos-Oré, Veronica Pravata, Raquel Pérez-Sen, Esmerilda G Delicado, Micha Drukker, Antonio R Artalejo, Silvia Cappello, Rosa Gómez-Villafuertes, Felipe Ortega
Published: 202610.1016/j.neuropharm.2025.110784
Abstract
The human neocortex represents a crucial evolutionary advance, the formation of which requires the tight and precise orchestration of both intracellular and extracellular signals. Structures grown in three-dimensional cultures, specifically human-ind…
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