NeuronImmunotherapyHumansNeoplasmsAnimalsT-Lymphocytes
Targeting tumor-associated nerves enhances cancer immunotherapy.
Canhui Cao
Published: 202510.1016/j.neuron.2025.09.005
Abstract
Tumor-associated nerves actively shape tumor immunity. In a recent issue of Nature, Baruch et al.1 show that cancer-induced nerve injury drives T cell exhaustion and undermines PD-1 blockade. Targeting this neuro-immune crosstalk is a promising strat…
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