NeuroImage
Longitudinal P2X7R and myelin PET reveal distinct neuroinflammatory and white matter signatures compared with TSPO PET and DTI-MRI in the TgF344-AD rat model.
Oscar Moreno, Izaro Fernández, Sandra Plaza-García, Daniel Padro, Zuriñe Baz, Pedro Ramos-Cabrer, Abraham Martín, Jordi Llop
Published: 202610.1016/j.neuroimage.2026.121753
Abstract
Emerging evidence links glial activation, particularly microglia, to Alzheimer's disease (AD) progression. While TSPO PET (positron emission tomography) imaging detects neuroinflammation, its limitations drive interest in alternative targets like the…
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