Neurochemistry internationalAnimalsPC12 CellsRatsCyclin-Dependent Kinase 5Mitochondria
BLF stimulates neuronal differentiation via activation of p35/CDK5 signaling and AMPK-mediated mitochondrial regulation.
Abdulkadir Cidem, Muhammet Oner, Gary Ro-Lin Chang, Chih-Ching Yen, Ke-Rong Chen, Shang-Hsun Yang, Ho Lin, Chuan-Mu Chen
Published: 202610.1016/j.neuint.2025.106106
Abstract
Lactoferrin (LF) is a multifunctional glycoprotein with established roles in non-neuronal cell growth and differentiation and has underexplored potential in neurodevelopment. Here, we investigated bovine lactoferrin (bLF) as a neurotrophic agent, sys…
Preview only. Read the full abstract at the source