Neurochemistry internationalAlzheimer DiseaseHumansCeramidesAnimalsAmyloid beta-Peptides
Assessing the critical role of ceramide in the pathogenesis of Alzheimer's disease and its clinical significance.
Yi-Wen Huang, Hua-Chen Chan, Jing-Yi Khoo, Mei-Lin Chan, Daniel Bender, Vinoth Kumar Ponnusamy, Abdel Ali Belaidi, Liang-Yin Ke
Published: 202610.1016/j.neuint.2025.106104
Abstract
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by amyloid-β (Aβ) deposition, tau hyperphosphorylation, and synaptic loss. Emerging evidence indicates that apolipoprotein E (APOE) polymorphism and dysregulated ceram…
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