Neurochemistry internationalHumansGlioblastomaApoptosisCell LineTumor
Transcription factor EB inhibition in response to genotoxic stress promotes apoptosis of glioblastoma cells.
Seung-Ho Park, Minseok Jeong, Min-Jeong Kong, Kyung-Chul Choi
Published: 202510.1016/j.neuint.2025.106087
Abstract
Glioblastoma multiforme (GBM), one of the most malignant brain cancers, responds poorly to chemotherapy and surgery. Transcription factor EB (TFEB) is markedly overexpressed in GBM cells. We investigated whether TFEB contributes to resistance to geno…
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