New biotechnology
Integration of strain and process optimization to increase autotrophic growth of engineered Komagataella phaffii.
Michael Baumschabl, Lisa Lutz, Marina Jecmenica, Özge Ata, Diethard Mattanovich
Published: 202510.1016/j.nbt.2025.11.010
Abstract
Synthetic autotrophs are a promising platform for sustainable bioproduction using CO2 as substrate. The methylotrophic yeast Komagataella phaffii has been engineered to use CO2 as the sole carbon source by integration of the Calvin-Benson-Bassham (CB…
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