Neurobiology of diseaseAnimalsMagnetic Resonance ImagingMiceInbred C57BLGlymphatic System
Dynamic contrast-enhanced MRI reveals glymphatic dysfunction in mice with depressive-like behavior.
Cui Lyu, Yong Xia, Yang Li, Jun Que, Feifan Han, Qin Guan, Yiming Wang, Bo Gao
Published: 202510.1016/j.nbd.2025.107169
Abstract
OBJECTIVE: This study aimed to investigate glymphatic system dysfunction in chronic unpredictable mild stress (CUMS)-induced depressive-like mice and its association with aquaporin-4 (AQP4) and astrocyte alterations using dynamic contrast-enhanced MR…
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