Neurobiology of diseaseAlzheimer DiseaseHumansMitophagyAnimalsMitochondria
Mitophagy in Alzheimer's disease and its potential as a therapeutic target.
Jiahua Wei, Tiegang Xiao, Jialu Lyu, Yueshuang Zhao, Yang Zhang, Xiangyu Du, Ying He, Mengqing Zhao, Xiaoyi Yang, Yutong Yao, Jun Ruan, Kaili Liu, Li Zhang, Jiangbo Zhao, Jun Xu
Published: 202510.1016/j.nbd.2025.107162
Abstract
Accumulation of damaged mitochondria is a well-established hallmark of age-related neurodegenerative disorders, including Alzheimer's disease (AD). Increasing evidence suggests that mitophagy, a selective autophagic degradation of damaged mitochondri…
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