Multiple sclerosis and related disordersHumansFemaleMaleAdultGlymphatic System
Extending the ALPS index: Associating whole-brain patterns with glymphatic-related diffusion metrics in multiple sclerosis.
Sascha D Santaniello, Gabriel Gonzalez-Escamilla, Markus Janko, Marc A Brockmann, Sergiu Groppa, Ahmed E Othman, Andrea Kronfeld
Published: 202510.1016/j.msard.2025.106835
Abstract
BACKGROUND: The glymphatic system (GS) in the perivascular spaces is key in the clearance of metabolic waste products from the brain and is impaired in neuroinflammatory conditions. Unfortunately, its in-vivo non-invasive examination is currently spa…
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