Multiple sclerosis and related disordersHumansMaleFemaleFatigueAdult
Assessment of changes in fatigue and cognitive functioning in the absence of progression independent of relapse activity.
Bonnie I Glanz, Tanuja Chitnis, Howard L Weiner, Brian C Healy
Published: 202510.1016/j.msard.2025.106786
Abstract
BACKGROUND: Progression Independent of Relapse Activity (PIRA) has become an important new outcome measure in MS clinical studies since it identifies disability accumulation that this not relapse related. Since PIRA focuses on changes in the expanded…
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