Molecular plant
Dephosphorylation and polyubiquitination of the histone variant H2AX coordinately terminate DNA damage signaling in Arabidopsis.
Xuerui Lu, Xiaodan Yu, Zhiping Deng, Zhichao Wang, Lvwen Zhang, Shixi Shi, Lili Wang, Shunping Yan
Published: 202510.1016/j.molp.2025.12.029
Abstract
Both activation and termination of DNA damage response (DDR) are essential to maintain genome stability. It is well-known that the histone variant H2AX is rapidly phosphorylated to activate DDR in eukaryotes. But how H2AX signaling is terminated rema…
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