Molecular metabolism
Single cell transcriptomics of human weight loss links adipocyte NPY1R to control of lipolysis.
Julius E R Grothen, Jaime M Martinez, Nikos Sidiropoulos, Lucas Massier, Danae Zareifi, Jiawei Zhong, Ida Davidsen, Jette W Platou, Jette Mandelbaum, Pia Rothe, Henning Hvid, Mads Grønborg, Christian Toft Madsen, Jens M Bruun, Mikael Rydén
Published: 202510.1016/j.molmet.2025.102305
Abstract
BACKGROUND: Combination of increased physical exercise and hypocaloric diet has long been recognized to improve cardiometabolic health and adipose tissue function, including lipid turnover. How such lifestyle interventions mediate benefits at the cel…
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