Molecular immunologyPyroptosisHumansMitochondriaAnimalsSignal Transduction
Mitochondria in pyroptosis: Mechanisms and implications.
Basmah M Eldakhakhny, Wesam H Abdulaal, Johra Khan, Amir Ajoolabady, Domenico Pratico, Suhad Bahijri, Jaakko Tuomilehto, Anwar Borai, Bonglee Kim, Jun Ren
Published: 202610.1016/j.molimm.2025.12.002
Abstract
Pyroptosis is an inflammatory, necrotic, and lytic form of programmed cell death, involving activation of inflammasome complexes, inflammatory caspases, and the cleavage of gasdermins. Gasdermins are a large family of pore-forming proteins with criti…
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