Molecular immunologyAnimalsPhosphofructokinase-2SepsisAcute Lung InjuryMice
ZBTB16 promotes the transcription of glycolytic enzyme PFKFB2 to participate in fibrogenesis in septic lung injury.
Zijian Tai, Chunting Wang
Published: 202510.1016/j.molimm.2025.10.007
Abstract
BACKGROUND: Sepsis is a severe systemic inflammatory response syndrome that leads to acute lung injury (ALI), which subsequently progresses to lung fibrosis. This study aims to investigate the role of zinc finger and BTB domain containing 16 (ZBTB16)…
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