Molecular cellAnimalsMitosisDNATranscription FactorsChromatin
Anchoring the acentric: How retention elements give ecDNA immortality.
Xing Kang, Haiyun Gan
Published: 202610.1016/j.molcel.2025.12.027
Abstract
In a recent Nature article, Venkat Sankar et al.1 uncover ecDNA harboring specific DNA sequences called retention elements, contact regions of mitotic chromosomes that are bookmarked by transcription factors and chromatin proteins to promote coordina…
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