Molecular cellEscherichia coliEscherichia coli ProteinsVirus ReplicationDNAViral
The Ppl protein senses 3'-hydroxyl DNA overhangs and NTP depletion to halt phage infection.
Zixiao Xu, Hongqiu Pu, Lixu Jiang, Zhiming Wang, Ka-Yiu Edwin Kong, Lianrong Wang, Shi Chen
Published: 202610.1016/j.molcel.2025.11.011
Abstract
The continuous battle between hosts and viruses leads to the development of numerous antiviral defense systems. The recent discovery of previously unrecognized defense modules has greatly expanded our understanding of the interaction between hosts an…
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