Molecular cellHumansRNA-Binding ProteinsAmyotrophic Lateral SclerosisAnimalsNuclear Matrix-Associated Proteins
Spheres, worms, and packing problems in the nanoscale assembly of ALS-linked protein Matrin-3.
Ashok A Deniz
Published: 202510.1016/j.molcel.2025.09.013
Abstract
Matrin-3 (MATR3) is an RNA-binding protein that forms higher-order assemblies and pathological inclusions associated with neurodegenerative diseases. In this issue of Molecular Cell, Sprunger et al.1 explore the assembly of MATR3 and find that it for…
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