Microbial pathogenesis
BvrR of Brucella initiates microglial inflammation through the activation of the IRE1 pathway.
Zhao Wang, Xinwen Yu, Dongni Ren
Published: 202610.1016/j.micpath.2026.108313
Abstract
Brucella-induced microglial inflammation plays a pivotal role in the neuropathology of neurobrucellosis. The virulence factor BvrR, critical for Brucella replication and survival within the host cell's endoplasmic reticulum (ER), has an undefined rol…
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