Microbial pathogenesis
Maxing Shigan decoction serves as a key component of Lianhua Qingwen in alleviating lung and gut injury by restoring gut microbiota homeostasis and inhibiting inflammation via TLR4/NF-κB and JAK2/STAT3 dual regulation.
Caiyun Yuan, Peipei Jin, Zhuo He, Jing Guo, Mingyu Xiong, Jiemeng Sun, Le Wang, Zixuan Wang, Ningxin Han, Wei Feng, Yunlong Hou, Hui Qi, Zhenhua Jia
Published: 202610.1016/j.micpath.2026.108285
Abstract
Lianhua Qingwen (LHQW), a clinically validated herbal medicine containing Maxing Shigan Decoction (MXSGT) and others, shows broad efficacy in various respiratory disease. However, its regulatory role on the gut-lung axis, particularly the contributio…
Preview only. Read the full abstract at the source