Microbial pathogenesisAcroleinEndopeptidasesPeptidoglycanHydrolysisGram-Negative Bacteria
Combination of endolysin LysK04 and cinnamaldehyde potentially inhibits Gram-negative pathogens via outer membrane disruption and peptidoglycan hydrolysis.
Harshitha N, Adrija Saha, Abhijith Mandal, Swati Rout, Sunil S More, Susweta Das Mitra
Published: 202610.1016/j.micpath.2025.108262
Abstract
Phage-derived endolysins are emerging as promising antibacterial agents due to their ability to enzymatically degrade the conserved peptidoglycan layer of bacterial cell walls. However, their exogenous application against Gram-negative bacteria is li…
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