Microbial pathogenesisHumansMalariaFalciparumGenetic Predisposition to DiseasePolymorphism
Immunomodulatory effects of the TIRAP/MAL rs8177374 (S180L) variant: Meta-Analytic evidence from severe and Plasmodium falciparum malaria.
Noelia Ivett González-Castillo, Sandra Guadalupe Prado-Rodríguez, Omar Iñiguez-Mosqueda, Liliana Íñiguez-Gutiérrez, Jorge Manuel Silva-Jara, Mariana Díaz-Zaragoza, Omar Graciano-Machuca
Published: 202610.1016/j.micpath.2025.108226
Abstract
BACKGROUND: The rs8177374 (S180L) polymorphism in TIRAP has been implicated in altered susceptibility to various infectious diseases, including malaria, though results across studies have been inconsistent. OBJECTIVE: To systematically review and met…
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