Microbial pathogenesisFerroptosisHemolysin ProteinsIronHumansReactive Oxygen Species
A review: Bacterial hemolysin-mediated iron dysregulation and immune cell damage synergistically drive ferroptosis.
Jiao Wang, Qibin Jiang, Songmao Wu, Wei Fan, Kun Peng, Keyu Zhou, Lu Xu, Defang Chen, Xiaoli Huang, Ping Ouyang, Yi Geng
Published: 202610.1016/j.micpath.2025.108130
Abstract
Hemolysin, a critical virulence factor of bacterial pathogens that disrupts host cell membranes, induces cytolysis and facilitates immune evasion during its infection. Ferroptosis, an iron-dependent form of regulated cell death (RCD), is characterize…
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