Current opinion in microbiology
tRNAs as toxin targets in phage defence and a focus of counter-defence against abortive infection.
Tom J Arrowsmith, Maria Puiu, Tim R Blower
Published: 202510.1016/j.mib.2025.102697
Abstract
Shutoff of host translation is a common immunity strategy employed by bacteria to defend against predatory bacteriophages. Many bacterial toxin-antitoxin systems specifically target and inactivate tRNAs to achieve translational inhibition, potentiall…
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