Metabolism: clinical and experimentalFoam CellsAtherosclerosisAnimalsMuscleSmooth
Meteorin-like protein inhibits vascular smooth muscle cell-derived foam cell formation and atherosclerosis via KIT- endoplasmic reticulum stress signaling.
Xu Chen, Xueying Jiang, Siyu Hou, Fengling Lai, Keqing Hu, Jie Li, Ting Yang, Xinxin Shen, Huimin Chen, Shen Chen, Xianfei Guo, Yan Zheng, Tao Xu, Guohai Su, Rong Huang
Published: 202610.1016/j.metabol.2025.156459
Abstract
OBJECTIVE: Vascular smooth muscle cell (VSMC)-derived foam cell formation is a major contributor to atherosclerosis progression and plaque instability. Meteorin-like protein (METRNL), a secreted organokine with known metabolic and anti-inflammatory e…
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