Med (New York, N.Y.)AdultFemaleHumansMaleMiddle Aged
Semaglutide for the treatment of cognitive dysfunction in major depressive disorder: A randomized clinical trial.
Sebastian Badulescu, Hartej Gill, Hiya Shah, Ryan Brudner, Lee Phan, Joshua D Di Vincenzo, Aniqa Tabassum, Michael Armanyous, Cristian-Daniel Llach, Joshua D Rosenblat, Roger S McIntyre, Rodrigo B Mansur
Published: 202610.1016/j.medj.2025.100916
Abstract
BACKGROUND: Evidence suggests that glucagon-like peptide 1 receptor agonists (GLP-1RAs) might have pro-cognitive effects. No prior study has evaluated the efficacy and safety of a GLP-1RA for the treatment of cognitive dysfunction in adults with majo…
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