Molecular and cellular endocrinologyHumansOvernutritionAlcohol DrinkingAnimalsFatty Liver
Interrelationship between alcohol consumption, overnutrition, and pharmacotherapy for liver steatosis: Considerations and proposals.
Rodrigo Valenzuela, Camila Farías, Yasna Muñoz, Jessica Zúñiga-Hernández, Luis A Videla
Published: 202610.1016/j.mce.2025.112676
Abstract
Alcoholism and overnutrition both contribute to the development of hepatic steatosis in humans. In alcoholic liver disease, steatosis is driven by (i) alcohol oxidation via alcohol dehydrogenase (ADH), which increases the NADH/NAD+ ratio, and (ii) in…
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