Mathematical biosciencesHepatitis BChronicHumansDNACircular
Modeling covalently closed circular DNA dynamics in assessing chronic hepatitis B prognosis.
Qiulin Huang, Qiang Li, Zaitang Huang, Yuming Wang, Guangyu Huang, Kaifa Wang, Wendi Wang
Published: 202510.1016/j.mbs.2025.109568
Abstract
The persistence of covalently closed circular DNA (cccDNA) in the nuclei of HBV-infected hepatocytes plays a critical role in the pathogenesis of chronic hepatitis B (CHB), and hepatitis B surface antigen (HBsAg) levels can be considered a surrogate…
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