Matrix biology : journal of the International Society for Matrix BiologyAnimalsFibronectinsMaleBone DensityHumans
Liver-derived, circulating plasma fibronectin regulates trabecular bone mass and bone formation in adult male mice and its levels in sera associates with bone density in aging men.
Mahdokht Mahmoodi, Claudie Berger, Mir-Hamed Nabavi, Yongjun Xiao, Lucie Canaff, Monica Pata, Jingjing Li, Mathieu Ferron, Monzur Murshed, David Goltzman, Suzanne N Morin, Mari T Kaartinen
Published: 202610.1016/j.matbio.2025.12.001
Abstract
Plasma fibronectin is a liver-derived glycoprotein that circulates at relatively high concentration and accumulates in tissues to form ECM. The role of plasma fibronectin in osteoblastogenesis, bone formation and remodeling has been suggested by many…
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