Molecular aspects of medicineHumansRetinal DiseasesCodonNonsenseRNA
The potential use of anti-codon engineered tRNAs (ACE-tRNAs) to treat nonsense variants causing inherited retinal diseases.
Asodu Sandeep Sarma, Dror Sharon
Published: 202610.1016/j.mam.2025.101443
Abstract
Inherited retinal diseases (IRDs) are clinically and genetically complex disorders that cause blindness in about one in 3450 individuals worldwide. More than 350 genes have been implicated in IRDs showing all possible inheritance patterns. Despite th…
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