Molecular aspects of medicineHumansEndogenous RetrovirusesAgingImmunityInnate
Emerging and Re-emerging viruses as triggers of human endogenous retrovirus activation: Implications for aging and age-related pathologies.
Yan Wu, Shuai Huang, Qian Sha, Jing Yu
Published: 202510.1016/j.mam.2025.101422
Abstract
The human genome contains a substantial legacy of ancient retroviral infections known as Human Endogenous Retroviruses (HERVs), composing 8 % of our DNA. In healthy young individuals, these elements are kept dormant by robust epigenetic mechanisms, p…
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