Mechanisms of ageing and developmentAgingHumansDNA MethylationMaleFemale
Compatibility and comparative analysis of chronological and biological aging between the legacy 450K and the EPIC v2.0 arrays.
Sven De Pourcq, Pei-Lun Kuo, Ann Zenobia Moore, Stefania Bandinelli, Steve Horvath, Luigi Ferrucci, Valeria Santini
Published: 202610.1016/j.mad.2025.112142
Abstract
Several epigenetic clocks based on DNA methylation arrays have been developed to evaluate biological aging. However, there is limited information on how the newer EPIC v2.0 arrays affect clock estimations, which lack probes initially present on legac…
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