Ferroptosis at high altitude: Interplay between hypobaric hypoxia and iron balance alteration in cells.

Ferroptosis is a regulated, non-apoptotic form of cell death, characterized by iron-dependent lipid peroxidation. It is typically driven by glutathione depletion and failure of antioxidant defenses such as glutathione peroxidase 4 (GPX4). This cell d…

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