Life sciencesAnimalsMiceKnockoutInbred C57BLUrinary Bladder
Loss of PINCH2 leads to myogenic urinary retention in mice.
Jiali Jin, Jiaxin Wang, Chunhong Cui, Jin Zhang, Gaohaer Kadeerhan, Zikuan Zhang, Wenmin Guo, Zhongji Jiang, Chuanyue Wu, Ling Guo, Dongwen Wang
Published: 202610.1016/j.lfs.2025.124137
Abstract
AIMS: Myogenic urinary retention is a common urological disorder characterized by diminished detrusor contractility, reduced muscle mass, and disorganized muscle bundles, yet its molecular mechanisms are poorly defined. The adaptor protein PINCH2 is…
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