Life sciencesHumansIon ChannelsFibrosisAnimalsMechanotransduction
Piezo-mediated mechanically activated currents in organ fibrosis: Novel mechanisms and therapeutic strategies.
Ling Dong, Li-Chan Lin, Sui Mao, Zhen-Yu Liu, Peng Liu, Rui Li, Hui Tao, Ye Zhang
Published: 202510.1016/j.lfs.2025.124050
Abstract
Organ fibrosis is one of the major challenges to global health. During the process of fibrosis, the abnormal accumulation of extracellular matrix (ECM) leads to changes in the mechanical microenvironment of tissues. The organ system is a highly compl…
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