Life sciencesAnimalsNedd4 Ubiquitin Protein LigasesMicePyroptosisArtesunate
Artesunate attenuates cerebral injury after cardiac arrest via inhibiting caspase-11-mediated pyroptosis through NEDD4.
Lu He, Wenbin Zhang, Yufeng Hu, Jinyu Zhu, Licai Liang, Huijuan Yang, Qijiang Chen, Jiefeng Xu, Mao Zhang
Published: 202510.1016/j.lfs.2025.124019
Abstract
Cerebral injury after cardiac arrest (CA) is a frequent cause of death and diminished quality of life among patients who have successfully undergone cardiopulmonary resuscitation (CPR); however, treatment options remain limited. Artesunate (Art), pri…
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