The Lancet. MicrobeMycobacterium tuberculosisWhole Genome SequencingHumansGenomeBacterial
Evaluating 12 automated, whole-genome sequencing analysis pipelines for Mycobacterium tuberculosis complex: a comparative study.
Ruan Spies, Derrick W Crook, Timothy E A Peto, Philip W Fowler, Robert Turner, Hieu Thai, James A Watson, Timothy M Walker
Published: 202510.1016/j.lanmic.2025.101210
Abstract
BACKGROUND: Reliance on complex, custom-built bioinformatics pipelines is a barrier to the implementation of whole-genome sequencing (WGS) of Mycobacterium tuberculosis in high-burden settings in some low-income and middle-income countries (LMICs). A…
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