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Cognitive changes in older adults receiving pharmacotherapy for treatment-resistant depression: a secondary analysis of the OPTIMUM randomised controlled trial.
Hanadi A Oughli, Nicholas J Ainsworth, Meryl A Butters, Patrick J Brown, Marie Anne Gebara, Torie R Gettinger, Jordan F Karp, Helen Lavretsky, Emily Lenard, J Philip Miller, Benoit H Mulsant, Ginger E Nicol, Charles F Reynolds, Michael Yingling, Eric J Lenze
Published: 202510.1016/j.lanhl.2025.100767
Abstract
BACKGROUND: The cognitive effects of various antidepressant strategies for treatment-resistant depression in older adults are unclear. We aimed to evaluate acute cognitive changes associated with various pharmacotherapy treatment strategies for treat…
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