Kidney international
Uremia and parathyroid hormone have distinct effects on bone protein and gene expression.
Carolina S Wagner, Rosilene M Elias, Thomas L Nickolas, Aline Martin, Marta Martinez-Calle, Ivone B Oliveira, Ana C Coelho, Luciene M Dos Reis, Vanda Jorgetti, Valentin David, Rosa M A Moysés
Published: 202610.1016/j.kint.2025.12.025
Abstract
INTRODUCTION: Chronic kidney disease (CKD)-associated osteoporosis is highly prevalent and increases the risk of fractures. Current therapy aims to preserve normal bone turnover, by maintaining parathyroid hormone (PTH) at relatively adequate levels.…
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