Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
The Genomic Landscape of NSCLC in Systemic Sclerosis Reveals Frequent TP53 Mutations and a Paucity of Actionable Oncogenes.
Igor Odintsov, Mark M Hammer, Biagio Ricciuti, Federica Pecci, Mark M Awad, Paul F Dellaripa, Lynette M Sholl
Published: 202510.1016/j.jtho.2025.10.008
Abstract
INTRODUCTION: Systemic sclerosis (SSc) is a chronic connective tissue disease associated with a significantly elevated and disproportionate risk of developing NSCLC, yet the underlying molecular drivers remain poorly understood. Specifically, it is u…
Preview only. Read the full abstract at the source