Journal of thermal biologyNeurogenesisHumansAnimalsBrain-Derived Neurotrophic FactorDepressive Disorder
Effects of heat environments on depressive disorders: Neurogenesis-mediated mechanisms.
Minghui Kong, Qiaoqiao Li, Xiaoyi Chen
Published: 202510.1016/j.jtherbio.2025.104304
Abstract
Heat may induce depressive disorders by affecting hippocampal neurogenesis. Heat stress may activate the hypothalamic-pituitary-adrenal (HPA) axis, leading to elevated glucocorticoid levels, which in turn cause hippocampal damage, suppress the expres…
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